Pilot freeze-dryer
Compact floor-standing unit for process optimisation and process development
Epsilon 2-6D LSCplus
The Epsilon 2-6D LSCplus freeze dryer is a general-purpose, high-performance laboratory and pilot unit for drying solid or liquid products in vials, ampoules, tubes, other glass containers or dishes.
The applications of the Epsilon 2-6D LSCplus freeze dryer include the drying of bacteria or cultures, viruses, blood plasma, serum fractions, antibodies, vaccines, medicines such as chloramphenicol or streptomycin, vitamins, biomass and plant extracts for biochemical tests.
The Epsilon 2-6D LSCplus is also ideal for product development and small-scale production activities.
Technical data
| Ice condenser capacity: | 6 kg |
| Ice condenser temperature: | –88 °C |
| Shelf dimensions: | 225 x 300 mm (W x D) |
| Number of shelves: | 1 to 6 |
| Shelf area: | 0,0675 m2 to 0,3375 m2 |
| Shelf spacing: | 249 mm to 31 mm |
| Shelf temperature: | –50 °C to +60 °C |
| GWP Index: | ≤ 6 |
| Shelf temperature accuracy: | max. ±1 °C |
| Cooling systems: | 2 independent systems, air cooled (optionally water cooled) |
| Ice condenser cooling system: | 2 compressors, 0.6 kW each, in cascade configuration |
| Shelf cooling system: | 1 compressor, 0,6 kW |
| Unit dimensions: | 1267 x 860 x 650 mm (H x W x D) |
Equipped with natural refrigerants*
As a leading manufacturer of freeze drying systems, we use natural refrigerants to provide sustainable and environmentally friendly freeze drying solutions. Our innovations help reduce environmental impact and build a greener future.
In 2009, we became one of the first manufacturers to convert our laboratory and pilot freeze dryers to nonflammable refrigerants. As a result, our freeze dryers have a particularly low Global Warming Potential (GWP) index.
* 50 Hz version, technichal changes reserved
WTMplus 2.0 – Wireless Temperature Measurement
The WTMplus 2.0 (wireless product temperature measurement system) avoids the disadvantages arising from the use of wired temperature sensors. It is significantly easier to use in practice. There is no need for temperature sensor cables or connectors inside the vacuum chamber. The wireless self-powered sensors are placed manually or automatically when the product vials or dishes are filled and report the corresponding product temperatures to the unit controller during the entire lyophilisation process.
Technical data
| Probe dimensions | Length: 21 mm plus 29 mm flexible antenna Diameter: 2.8 mm |
| Temperature measuring range | –60 °C to +135 °C |
| Measurement accuracy | ±1,0 K |
| Temperature resolution | 0.1 K |
Comparative pressure measurement
In addition to product temperature measurement and pressure rise testing, the simultaneous use of two vacuum sensors with different measuring principles can provide information about the progress of the drying process. The commonly used Pirani gauge indicates higher absolute pressures at the start of the primary drying phase because its operation is dependent on the gas type and large amounts of water vapour are released at the start of the primary drying phase. By contrast, capacitive pressure sensors are independent of the gas type. The approaching end of the primary drying phase, which occurs when there is no longer a significant concentration of water vapour, is indicated by the gradual approach of the two pressure curves to each other during the process.
Sample extraction system
The sample extraction system allows individual sample containers to be removed under vacuum during the drying process without interrupting the drying process. This is done by using a gripper arm to pick up the sample container, close it, and remove it through a vacuum lock. This allows individual sample containers or vials to be removed from the freeze dryer at defined intervals. The samples removed through the vacuum lock can be investigated and analysed in parallel with the ongoing process. This allows the progress of the process to be measured and documented in detail.
Technical data
| Sample containers/vials: | 6R to 30R Max. 50H |
| Coupling flange: | DN 160 clamp |
| Gripper working range: | 200 mm |
| Stoppering device: | Teflon-coated plunger |
| Vacuum lock: | DN50 |
| Materials: | Stainless stell 1.4404 and 1.4435, Teflon, Borosilicate glass |
| Visualisation: | Direct or with a digital camera, lighting fixture and monitor |